100-300 AD: The Romans introduce improved viticulture to the Douro.

1703: The Methuen Treaty opens up new markets for port wine exports to Britain.

1756: The Douro becomes the first protected wine region in the world.

1868: Arrival of Phylloxera in the Douro.

2001: The Alto Douro Wine region is listed as a UNESCO World Heritage site and Cultural Landscape.

2014: 3 out of the top 5 in the Wine Spectator “Top 100 Lists” are Douro wines.